Associate Manager-Computational Biology

Where

Tarrytown, NY

What you'll be doing

Develop and implement computational methods and pipelines for functional variant interpretation, including loss-of-function variation, utilizing multiple molecular data types (WES, WGS, RNA-seq, methyl-seq, etc) from in-house and publicly available resources. Interface with analytical genetics, genome informatics, and other team members in translational genetics to provide general computational biology and informatics support for translational genetics activities spanning the full range of genomic analyses. Prioritize markers discovered through genetic association studies by incorporating gene expression, epigenetic, and other omics data sets to provide functional genetic context for these discoveries. Detect and utilize expression quantitative trait loci (eQTL) to identify causal relationships between genotype and phenotype. Examine gene expression phenotypes of in vitro and in vivo experiments used to validate candidate genes. Survey the literature and attend conferences to incorporate discoveries and findings from the broader genetics community into study opportunities and considerations internally. Communicate and report study findings and analyses with leadership, administration, and collaborators.

What your background should be

This position required 5 years experience in computational biology, and functional genomics, with a bioinformatics focus. Strong statistical computing background, including analysis and visualization in one of R, SAS, python, Matlab, etc. Expert programming skills, including scripting (Perl, Python) and non-scripting languages (Java, C++). Must be comfortable in a Linux environment. Demonstrated ability to design and implement computational workflows.

Required Schooling / Training

PhD degree.

Who is the client company

This is a biotechnology company.

If you are interested in this position, send your resume to apply@kochdavis.com